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Methodological approaches and magnitude of the clinical unmet need associated with amotivation in mood disorders.

Identifieur interne : 002152 ( Main/Exploration ); précédent : 002151; suivant : 002153

Methodological approaches and magnitude of the clinical unmet need associated with amotivation in mood disorders.

Auteurs : Joseph R. Calabrese [États-Unis] ; Maurizio Fava [États-Unis] ; George Garibaldi [Suisse] ; Heinz Grunze [Royaume-Uni] ; Andrew D. Krystal [États-Unis] ; Thomas Laughren [États-Unis] ; Wayne Macfadden [Suisse] ; Robert Marin [États-Unis] ; Andrew A. Nierenberg [États-Unis] ; Mauricio Tohen [États-Unis]

Source :

RBID : pubmed:25113957

Descripteurs français

English descriptors

Abstract

There is growing research interest in studying motivational deficits in different neuropsychiatric disorders because these symptoms appear to be more common than originally reported and negatively impact long-term functional outcomes. However, there is considerable ambiguity in the terminology used to describe motivational deficits in the scientific literature. For the purposes of this manuscript, the term "amotivation" will be utilised in the context of mood disorders, since this is considered a more inclusive/appropriate term for this patient population. Other challenges impacting the study of amotivation in mood disorders, include: appropriate patient population selection; managing or controlling for potential confounding factors; the lack of gold-standard diagnostic criteria and assessment scales; and determination of the most appropriate study duration.

DOI: 10.1016/j.jad.2014.06.056
PubMed: 25113957


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">There is growing research interest in studying motivational deficits in different neuropsychiatric disorders because these symptoms appear to be more common than originally reported and negatively impact long-term functional outcomes. However, there is considerable ambiguity in the terminology used to describe motivational deficits in the scientific literature. For the purposes of this manuscript, the term "amotivation" will be utilised in the context of mood disorders, since this is considered a more inclusive/appropriate term for this patient population. Other challenges impacting the study of amotivation in mood disorders, include: appropriate patient population selection; managing or controlling for potential confounding factors; the lack of gold-standard diagnostic criteria and assessment scales; and determination of the most appropriate study duration.</div>
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